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Used with adjectives:
"
Be careful with poisonous substances around the house."
(poisonous, harmful, toxic, hazardous, dangerous)
"
He was in possession of heroin and other illegal substances."
(illegal, banned, controlled, illicit, prohibited)
"
The athlete was caught using a performance-enhancing substance."
(performance-enhancing, synthetic)
"
She claimed that she was using a harmless substance."
(harmless, natural, organic, pure)
"
We found some sticky substances on the floor."
(sticky, gooey, oily, powdery, slimy, foreign, unknown, chemical)
"
He never says anything with real substance."
(real)
"
Their research has provided added substance to the argument."
(added)
Used with verbs:
"
The pesticide contains harmful substances."
(contains)
"
The athlete has been using illegal substances for a long time."
(using, abusing, taking)
"
All of the accusations have no substance."
(have)
"
The results of the study give substance to their theory."
(give, add, lend)
"
Your theory lacks substance."
(lacks)
Used with nouns:
"
He has a history of substance abuse."
(abuse, use, addiction)
Used with prepositions:
"
There is no real substance in his story."
(in, to)
"
She has a history of substance abuse."
(of)
"
Those accusations are without substance."
(without)
"
She writes poems with true substance."
(with)
